• Qualifications: MSc, PhD
  • Department: Assistant Professor
  • Designation: Department of Biotechnology / Applied Genetics
  • Years of Experience: 9 Years (Research), 1 Year (Teaching)
  • Email: naveenbio10@gmail.com

Academic and Professional Achievements

Research Interest

Cancer Biology, Cell Science and Environmental Biotechnology.

Ph.D. Thesis title: “Studies on the differentiation of human choriocarcinoma cells: Role of nuclear receptors and protein kinase pathways”

Awards / Scholarship / Fellowships
  1. CSIR – Senior Research Fellowship
  2. Govt. of Karnataka, Vidyasiri Scholarship
  3. DST-PURSE Technical assistant fellowship
Peer-Reviewed Scientific Publications
  1. Naveen Kumar M., Babu R.L., Rajeshwari H. Patil, Kiran Kumar K. M., Shubha M. Hegde, Rashmi Nagesh, Kavya K., Govindarajan T. Ramesh, S. Chidananda Sharma, Srinivas C. (2019) Protein kinases orchestrate cell cycle regulators in differentiating BeWo choriocarcinoma cells. Molecular and cellular biochemistry. 452(1-2):1–15.
  2. Rajeshwari H Patil, Naveen Kumar M., Kiran Kumar K.M., Rashmi Nagesh, Kavya K., Babu R.L., Govindarajan T. Ramesh, and S. Chidananda Sharma. (2018) Dexamethasone inhibits inflammatory response via down regulation of AP-1 transcription factor in human lung epithelial cells, Gene, 645: 85-94.
  3. Kavya Krishnappa, Naveen Kumar Mallesh, Srikantaradhya Chidananda Sharma, Doddamane Manjulakumari. (2017) Midostaurin inhibits hormone-refractory prostate cancer PC-3 cells by modulating nPKCs and AP-1 transcription factors and their target genes involved in cell cycle, Frontiers in Biology, 12(6): 421-429.
  4. Shubha M. Hegde, Naveen Kumar M., Manjunath K, and S. Chidananda Sharma. (2017) Role of NF-kB transcription factors, cell-cycle regulators and apoptotic genes in proliferation of MCF-7 cells. International Journal of Pharma and Bio Sciences, 8(2): (B) 553-561.
  5. Kavya K., Naveen Kumar M., Rajeshwari H Patil, Shubha M Hegde, Kiran Kumar K.M., Rashmi Nagesh, Babu R.L., Govindarajan T. Ramesh and S. Chidananda Sharma. (2017) Differential expression of AP-1 transcription factors in human prostate LNCaP and PC-3 cells: role of Fra-1 in transition to CRPC status. Molecular and cellular biochemistry, 433(1-2): 13-26.
  6. Rashmi Nagesh, Kiran Kumar K. M, Naveen Kumar. M, Rajeshwari Patil, Kavya K, Babu R L, Govindarajan T. Ramesh and Chidananda Sharma. (2017) Aqueous areca nut extract induces oxidative stress in human lung epithelial A549 cells: Probable role of p21 in inducing cell death. Gene Reports, 6: 103-111.
  7. Kiran Kumar K. M, Naveen Kumar. M, Rajeshwari Patil, Rashmi Nagesh, Shubha M. Hegde, Kavya K, Babu R L, Govindarajan T. Ramesh and Chidananda Sharma. (2016) Cadmium induces oxidative stress and apoptosis in lung epithelial cells. Toxicology Mechanisms and Methods, 26(9): 658-666.
  8. Shubha M. Hegde, Naveen Kumar. M, Kavya K, Kiran Kumar K. M, Rashmi Nagesh, Rajeshwari Patil, Babu R L, Govindarajan T. Ramesh and Chidananda Sharma. (2016) Interplay of nuclear receptors (ER, PR, and GR) and their steroid hormones in MCF-7 cells. Molecular and cellular Biochemistry, 422(1-2): 109-120.
  9. Rajeshwari Patil, Babu R L, Naveen Kumar. M, Kiran Kumar K. M, Shubha M. Hegde, Rashmi Nagesh, Govindarajan T. Ramesh and Chidananda Sharma. (2015) Anti-inflammatory effect of apigenin on LPS induced pro-inflammatory mediators and AP-1 factors in human lung epithelial cells. Inflammation, 39(1): 138-147.
  10. Rajeshwari Patil, Naveen Kumar. M, Babu R L., and Chidananda Sharma. (2015) Anti-inflammatory effect of plant extracts on LPS induced pro-inflammatory cytokines in A549 cells. Journal of Acute Disease, 5(2): 12-20.
  11. Rajeshwari Patil, Babu R L, Naveen Kumar. M, Kiran Kumar K. M, Shubha M. Hegde, Govindarajan T. Ramesh and Chidananda Sharma. (2015) Apigenin inhibits PMA induced expression of mRNAs of pro-inflammatory cytokines and AP-1 factors in A549 cells. Molecular and cellular Biochemistry, 403(1-2): 95-106.
  12. Shubha M. Hegde, Babu R L, Vijayalakshmi E, Rajeshwari Patil, Naveen Kumar. M, Kiran Kumar K. M, Rashmi Nagesh, Kavya K and Chidananda Sharma. (2015) Biosorption of hexavalent chromium from aqueous solution using chemically modified Spirulina platensis algal biomass: An ecofriendly approach. Desalination and Water Treatment, 57(18): 1–10.
  13. Babu, R.L., Vijayalakshmi, E., Naveen Kumar. M., Patil, R.H., Devaraju, K.S., and Sharma, S.C. (2013) Biosorption of Chromium (VI) and Lead (II): Role of Spirulina platensis in the Treatment of Industrial Effluent. Bioremediation Journal, 17(4): 231-239.
  14. Babu R L, Vijayalaksmi E, Naveen Kumar. M, Rajeshwari H. Patil and S. Chidananda Sharma. (2013) Blocking of CDK4 gene expression by antisense oligos induce apoptosis and decreases the proliferation of A549 cells. International Journal of Scientific Research, 2(8): 51-53.
  15. Babu R.L, Naveen Kumar. M, Patil, R.H, Devaraju, K.S, Ramesh, G.T, and Sharma, S.C. (2013) Effect of estrogen and tamoxifen on the expression pattern of AP-1 factors in MCF-7 cells: role of c-Jun, c-Fos, and Fra-1 in cell cycle regulation. Molecular and cellular biochemistry, 380(1-2): 143-151.

Book chapter: Babu R.L and Naveen Kumar. M. Cell Signalling and apoptosis in animals in “Advances in Animal Genomics” edited by Mondal and Singh, Publication due on January, 2020. Elsevier Inc. https://editorial.elsevier.com/app/book?bookId=ab53b398-75f4-4895-b9d6-67cad9b14372

Papers published and presented in the Conference Proceedings

  1. Naveen Kumar M., S. Chidananda Sharma and Srinivas C. Glucocorticoid Receptor-mediated regulation of Activator Protein-1 transcription factors and cell cycle regulators in placental BeWo choriocarcinoma cells. “1st International Conference on Life, Chemical, and Health Sciences”. Organized by the Ramaiah College of Arts, Science and Commerce, Bengaluru and Karnataka Science and Technology (KSTA), Department of Science and Technology, Govt. of Karnataka. Oral Presentation 24th and 26th October, 2019.
  2. Naveen Kumar M., S. Chidananda Sharma and Srinivas C. Coleus forskohlii extract forskolin regulates the differentiation of human placental choriocarcinoma cells via cAMP-activated PKA cascade. “National Conference on Phytochemicals and Microbial Bioactive Compounds – Role in Agriculture and Human welfare”. Organized by the Department of Microbiology and Biotechnology, Bangalore University, Bengaluru. Oral Presentation 3rd and 4th October, 2019.
  3. Naveen Kumar M., S. Chidananda Sharma and Srinivas C. Protein kinases regulate proliferation and differentiation of human placental cells. “11th Annual Conference of Karnataka Science and Technology Academy in association with NMKRV College for Women, Bengaluru on Theme ‘New Vistas in Science and Technology for Common Good’. Poster Presentation 1st and 2nd February 2019.
  4. Naveen Kumar M., S. Chidananda Sharma and Srinivas C. Effects of Forskolin and PMA on the differentiation and cell cycle regulation of human placental choriocarcinoma cells. “National Conference on Science and Technology for inclusive development”. Organized by the Gulbarga University, Kalaburagi and Karnataka Science and Technology (KSTA), Department of Science and Technology, Govt. of Karnataka. Poster Presentation 6th and 7th March 2018.
  5. Babu R L, Naveen Kumar M, Rajeshwari H Patil, Kiran Kumar K M, Govindarajan T Ramesh and S. Chidananda Sharma. Forskolin inhibits PMA induced expression of mRNAs of AP-1 factors (c-Jun/c-Fos and Fra1) in MCF-7 cells. Antisense oligos of c-Jun and c-Fos inhibits the cell proliferation. “National conference on Cell mechanics and interactions at the physics biology interface”, Department of Physics and DST-PURSE Programme, Bangalore University, Bengaluru. Poster Presentation. 30th and 31st August 2013.
Workshops/ Seminars/ Symposiums – Attended
  1. Participated in Science Academies Lecture Workshop on “Nanomaterials-Applications in Biotechnology” Organized by Dept. of Biotechnology, Ramaiah Institute of Technology, Bengaluru. 29th and 30th August 2019.
  2. Participated in Symposium on “Healthy Life style and Human Welfare”, Organized by the UGC-CPEPA and Department of Zoology, Bangalore University, Bengaluru. 18th and 19th November 2014.
  3. Participated in Indo-UK seminar on opportunities in Biotechnology, Organized by Department of Microbiology and Biotechnology, Bangalore University and British Council, Chennai. 28th September 2013.
  4. Participated in National workshop on “Application of Bioinformatics in medicine”, Organized by Department of Bioinformatics and Biotechnology, Akkamahadevi Women’s University, (KSWU), Bijapur, 586108. 8th and 9th January 2013.
  5. Participated in National workshop on “Frontier in cell biology and Biotechnology” Department of Microbiology and Biotechnology and DST-PURSE Programme, Bangalore University, Bangalore. 28th and 29th December 2012.